CDI Environmental Hygiene program:
- 302,000 healthcare associated Clostridium difficile infections per year (both acute and long-term care)
- 5000 hospitals plus 15,000 nursing homes (2010)=15.1 infections per facility per year (302,000 x .20)
- If we are in 5000 hospitals we are impacting 75,500 CDI infections per year.
- If we prevent 5% we will prevent 3775 infections per year.
Center for Infectious Disease Research and Policy (CIDRAP)
Centers for Disease Prevention and Control (CDC)
New England Journal of Medicine (NEJM)
CDI mortality is 6-30%
Hota, S. S., Achonu, C., Crowcroft, N. S., Harvey, B. J., Lauwers, A., & Gardam, M. A. (2012). Determining Mortality Rates Attributable to Clostridium difficile Infection. Emerging Infectious Diseases, 18(2), 305-307.
1132 deaths avoided per year (3775 x .30)
MRSA, Hand Hygiene and Environmental Hygiene programs:
14,156 Healthcare onset invasive MRSA infections per year in US.
Malani PN. National Burden of Invasive Methicillin-Resistant Staphylococcus aureus Infection. JAMA. 2014;311(14):1438–1439. doi:10.1001/jama.2014.1666
Improved hand hygiene compliance has been demonstrated to reduce MRSA infection by 50% in US.
World Health Organization Table: Key studies assessing the effect of hand hygiene interventions on MDROs’ transmission and/or infection
MRSA acquisition has been shown to decrease by half when cleaning improved from 42% to 72% using DAZO in an Ecolab-like program
Datta R, Platt R, Yokoe DS, Huang SS. Environmental cleaning intervention and risk of acquiring multi-drug resistant organisms from prior room occupants. Arch Intern Med. 2011;171(6):491-494.
7078 MRSA infections avoided by Hand Hygiene compliance program (14,145 x .50)
In hospital all-cause mortality associated with MRSA is 21%
Dantes R, Mu Y, Belflower R, Aragon D, Dumyati G, Harrison LH, Lessa FC, Lynfield R, Nadle J, Petit S, Ray SM, Schaffner W, Townes J, Fridkin S, . National Burden of Invasive Methicillin-Resistant Staphylococcus aureus Infections, United States, 2011. JAMA Intern Med. 2013;173(21):1970–1978.
1486 deaths avoided using Hand Hygiene Compliance program (7078 x .21)